Research

Translational regulation of gene expression mediated by uORFs

I first started this topic in the last years of my PhD, while trying to understand the regulation exerted by CPuORF33 on AtHB1. In 2018 I received a Long Term EMBO-Fellowship to continue this project, focusing on understanding the molecular mechanism behind uORFs translational regulation and its role in temperature sensing.

Research articles:

A uORF represses the transcription factor AtHB1 in aerial tissues to avoid a deleterious phenotype.

Ribone PA*, Capella M*, Arce AL, Chan RL. Plant phys. 2017. doi:10.1104/pp.17.01060

HD-Zip I function in the development of Arabidopsis thaliana

I did my Ph.D. thesis under the supervision of Dr. Raquel L. Chan, in the Agrobiotechnology Institute of Litoral. During this time, I studied three members of the HD-Zip I family of transcription factors in plants: AtHB13, AtHB23 and AtHB1.

Research articles:

The functional characterization of the homeodomain-leucine zipper I transcription factor AtHB13 reveals a crucial role in Arabidopsis development.

Ribone PA, Capella M, Chan RL. J. Exp. Bot. 2015. 66 (19): 5929-5943

Arabidopsis thaliana HomeoBox 1 (AtHB1), a Homedomain-Leucine Zipper I (HD-Zip I) transcription factor, is regulated by PHYTOCHROME-INTERACTING FACTOR 1 to promote hypocotyl elongation.

Capella M, Ribone PA, Arce AL, Chan RL. New Phytol. 2015 Apr 10. doi: 10.1111/nph.13401.

JUNGBRUNNEN1 confers drought tolerance downstream of the HD-Zip I transcription factor AtHB13.

Motlagh SE*, Ribone PA*, Thirumalaikumar VP, Allu AD, Chan RL, Mueller-Roeber B, Balazadeh S. Front. Plant Sci. 2015. doi:10.3389/fpls.2017.02118.

AtHB23 participates in the gene regulatory network controlling root branching and reveals differences between secondary and tertiary roots.

Perotti MF, Ribone PA, Cabello JV, Ariel FD, Chan RL. Plant Journal. 2019. doi: 10.1111/tpj.14511

A matter of quantity: Common features in the drought response of transgenic plants overexpressing HD-Zip I transcription factor.

Romani F, Ribone PA, Chan RL. Plant Science. 2016. Doi:10.1016/j.plantsci.2016.03.004.

A Predictive Coexpression Network Identifies Novel Genes Controlling the Seed-to-Seedling Phase Transition in Arabidopsis thaliana.

Silva A, Ribone PA, Chan RL, Ligterink W, Hilhorst HW. Plant phys. 2016. 170 (4) 2218-2231

Other collaborations

Research articles:

Expression and function of AtMBD4L, the single gene encoding the nuclear DNA glycosylase MBD4L in Arabidopsis.

Nota F, Cambiagno DA, Ribone PA, Alvarez ME. Plant Science. 2015. doi:10.1016/j.plantsci.2015.03.011.

Building a pathway for diversity in plant sciences in Argentina: highlighting the work of women scientists through virtual activities

Auge GA, de Leone MJ, Deanna R, Oliferuk S, Ribone PA, Welchen E. BioRxiv. 2020

doi:10.1016/j.plantsci.2015.03.011.

It takes a village - overcoming gender-biased mentorship in academia.

Deanna, R., Baxter, I., Chun, K. P., Merkle, B. G., Zuo, R., Diele-Viegas, L. M., … Auge, G. OSF Preprints. 2020

https://doi.org/10.31219/osf.io/25h7p

2050: A New World—Observations from a Policy-Making Board Game for Climate Change Engagement

Bentley L, Palate S, Ribone PA, Tennyson EM. Proceedings. 1st International Electronic Conference on Plant Science. 2020

Book chapters and reviews

Plant transcription factors from the Homeodomain-Leucine Zipper family I. Role in development and stress responses.

Perotti MF*, Ribone PA*, Chan RL. IUBMB Life. 2017. 69:280-289.

What do we know about homeodomain–leucine zipper I transcription factors? Functional and biotechnological considerations.

Ribone PA, Capella M, Arce AL, Chan RL. In: González D. Plant Transcription Factors. Evolutionary, structural and functional aspects. Elsevier. ISBN: 978-0-12-800854-6.

Homeodomain–Leucine zipper transcription factors: Structural features of these proteins, unique to plants.

Capella M, Ribone PA, Arce AL, Chan RL. In: González D. Plant Transcription Factors. Evolutionary, structural and functional aspects. Elsevier. ISBN: 978-0-12-800854-6.